Enterohaemorrhagic Escherichia coli infection and haemolytic uraemic syndrome become notifiable in Germany

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Sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- causes another outbreak of haemolytic uraemic syndrome in children.

An outbreak of haemolytic uraemic syndrome (HUS) among children caused by infection with sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- (SF EHEC O157:H-) occurred in Germany in 2002. This pathogen has caused several outbreaks so far, yet its reservoir and routes of transmission remain unknown. SF EHEC O157:H- is easily missed as most laboratory protocols target the more common ...

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Haemolytic uraemic syndrome associated with a family cluster of enterohaemorrhagic Escherichia coli.

In early 1995 an outbreak of 23 cases of haemolytic uraemic syndrome (HUS) occurred in children (ranging from four months to 12 years of age) in South Australia.1 Twenty of the cases were managed in a tertiary paediatric hospital in Adelaide, where 18 (90%) required dialysis.2 A 4-year-old died and 12 months after discharge 5 of the surviving children still had significantly impaired renal func...

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Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

OBJECTIVE To evaluate the effect of different treatment strategies on enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome. DESIGN Multicentre retrospective case-control study. SETTING 23 hospitals in northern Germany. PARTICIPANTS 298 adults with enterohaemorrhagic E coli induced haemolytic uraemic syndrome. MAIN OUTCOME MEASURES Dialysis, seizures, mechanica...

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Cytokines in haemolytic uraemic syndrome associated with verocytotoxin-producing Escherichia coli infection.

The proinflammatory cytokines tumour necrosis factor-alpha (TNF-alpha) interleukin (IL)-1 beta, IL-6, and IL-8 were measured in plasma and urine samples from 19 children with verocytotoxin-producing Escherichia coli (VTEC) induced haemolytic uraemic syndrome (HUS) and 30 controls. TNF-alpha was detected in the plasma of two cases and one control; IL-6 in the plasma of one, and the urine of two ...

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Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study.

BACKGROUND In an ongoing outbreak of haemolytic uraemic syndrome and bloody diarrhoea caused by a virulent Escherichia coli strain O104:H4 in Germany (with some cases elsewhere in Europe and North America), 810 cases of the syndrome and 39 deaths have occurred since the beginning of May, 2011. We analysed virulence profiles and relevant phenotypes of outbreak isolates recovered in our laborator...

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ژورنال

عنوان ژورنال: Weekly releases (1997–2007)

سال: 1999

ISSN: 9999-1233

DOI: 10.2807/esw.03.07.01453-en